Introduction.The aim of the present study was to determine the effects of vitamins D and E on the proliferation, morphology, and differentiation of human dental pulp stem cells (hDPSCs).Methods.In this in vitro experimental study, hDPSCs were isolated, characterized, and treated with vitamins D and E, individually and in combination, utilizing diff
Background: Hypoxia and consequent production of vascular endothelial growth factor A (VEGFA) promote blood vessel leakiness and edema in ocular diseases.Anti-VEGFA therapeutics may aggravate hypoxia; therefore, therapy development is Peels needed.Methods: Oxygen-induced retinopathy was used as a model to test the role of nitric oxide (NO) in patho
During cross-presentation, exogenous antigens (i.e.intracellular pathogens or tumor cells) are internalized and processed within the endocytic system and also by the proteasome in the cytosol.Then, antigenic peptides are associated with Major Histocompatibility Complex (MHC) class I molecules and these complexes transit to the plasma membrane in or
Abstract High recidivism rates indicate that current forms of imprisonment may be an ineffective response to problems that mainly burden those ensconced in poverty and marginalization.Homelessness, unemployment, racial disparities, drug use, and mental illness, disappear from public view when the afflicted individuals are relegated to a life behind